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Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1

2021-12-05

Abstract excerpt

Broadly neutralizing antibodies (bNAbs) are promising targets for vaccination and therapy against HIV. Passive infusions of bNAbs have shown promise in clinical trials as a potential alternative for anti-retroviral therapy. A key challenge for the potential clinical application of bnAbs is the suppression of viral escape, which is more effectively achieved with a combination of bNAbs. However, identifying an optim...

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Literature Corpus work
a8ff2f38-282c-5b98-8ed0-23543d5e478d
DOI
10.1101/2021.12.03.21267269
Open publication

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Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1DOI 10.1101/2021.12.03.21267269
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