Article

Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention

2021-07-28

Abstract excerpt

Broadly neutralizing antibodies are promising agents to prevent HIV infection and achieve HIV remission without antiretroviral therapy (ART). As learned from effective ART, HIV viral diversity necessitates combination antibody cocktails. Here, we demonstrate how to optimally choose the ratio within combinations based on the constraint of a total dose size. Optimization in terms of prevention efficacy outcome requi...

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Literature Corpus work: 83d74641-a88a-5131-b4d6-3e5fb0837777
DOI: 10.1101/2021.07.26.21261134

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