Article

Inhibition of EGFR/ErbB does not protect against <i>C. difficile</i> toxin B

2024-05-14

Abstract excerpt

Clostridioides difficile is a common cause of diarrhea and mortality, especially in immunosuppressed and hospitalized patients. C. difficile is a toxin-mediated disease, but the host cell receptors for C. difficile toxin B (TcdB) have only recently been revealed. Emerging data suggest TcdB interacts with receptor tyrosine kinases during infection. In particular, TcdB can elicit Epidermal Growth Factor Receptor (...

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Literature Corpus work: a8d54026-8ea5-587e-8459-610ac9a8ebe7
DOI: 10.1101/2024.05.13.594035

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