Article
Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic<i>Bacteroides fragilis</i>Using Cefoxitin Treatment
21 Feb 2016
Abstract excerpt
BACKGROUND: Chronic inflammation and composition of the colon microbiota have been associated with colorectal cancer in humans. The human commensal enterotoxigenic Bacteroides fragilis (ETBF) is linked to both inflammatory bowel disease and colorectal cancer and, in our murine model, causes interleukin 17A (IL-17A)-dependent colon tumors. In these studies, we hypothesized that persistent colonization by ETBF is...
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