Article
Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine.
Gastroenterology - 1 Aug 2003
Savidge Tor C, Pan Wei-Hua, Newman Paul, O'brien Michael, Anton Pauline M, Pothoulakis Charalabos
Abstract excerpt
BACKGROUND & AIMS: Clostridium difficile causes antibiotic-associated diarrhea and pseudomembranous colitis, diseases afflicting millions of people each year. Although C. difficile releases 2 structurally similar exotoxins, toxin A and toxin B, animal experiments suggest that only toxin A mediates diarrhea and enterocolitis. However, toxin A-negative/toxin B-positive strains of C. difficile recently were isolated...
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