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The UK BiLEVE and Mendelian randomisation: Using multivariable instrumental variables to address “damned if you, dammed if you don’t” adjustment problems

2022-10-27

Abstract excerpt

<h4>Objective</h4> To explore the use of multivariable instrumental variables to resolve the “dammed if you do, dammed if you don’t” adjustment problem created for Mendelian randomisation (MR) analysis using the smoking or lung function related phenotypes in the UK Biobank (UKB). <h4>Result</h4> “dammed if you do, dammed if you don’t” adjustment problems occur when both adjusting and not-adjusting for a variable w...

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Literature Corpus work
a8ba3344-f5f3-54ca-aa7b-f745d821d35e
DOI
10.1101/2022.10.25.22281084
Open publication

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The UK BiLEVE and Mendelian randomisation: Using multivariable instrumental variables to address “damned if you, dammed if you don’t” adjustment problemsDOI 10.1101/2022.10.25.22281084
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