Article

Re-evaluating the robustness of Mendelian randomisation to measurement error

2022-10-04

Abstract excerpt

<h4>Background</h4> Mendelian randomisation (MR) uses germline genetic variation as a natural experiment to investigate causal relations between traits. MR is robust to non-differential random measurement error in exposures or outcomes. However, the effect of differential measurement error, and non-differential measurement error on the variant selection process, remains unclear. <h4>Methods</h4> We use Monte-Carlo...

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Literature Corpus work: b00c4a21-06e8-579e-9e55-7941fe0a328d
DOI: 10.1101/2022.10.02.22280617

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