Article

Testing the principles of Mendelian randomization: Opportunities and complications on a genomewide scale

2017-04-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Mendelian randomization (MR) uses genetic variants as instrumental variables to assess whether observational associations between exposures and disease reflect causal relationships. MR requires genetic variants to be independent of factors that confound observational associations. <h4>Methods</h4> Using data from the Avon Longitudinal Study of Parents and Children, associat...

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Literature Corpus work: 93d6a60b-a697-527a-9abc-ffe03a6a25c6
DOI: 10.1101/124362

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