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Article

A Guide to Understanding Mendelian Randomization Studies

19 Jul 2024

Abstract excerpt

Epidemiology provides a powerful framework for characterizing exposure-disease relationships, but its utility for making causal inferences is limited because epidemiologic data are observational in nature and subject to biases stemming from undetected confounding variables and reverse causation. Mendelian randomization (MR) is an increasingly popular method used to circumvent these limitations. MR uses genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39030941
DOI: 10.1002/acr.25400

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