Article

Resolving the immune response across clonal cancer evolution in situ with whole transcriptome profiling

2026-08-07

Abstract excerpt

Single-cell spatial transcriptomics is now central to studying tumors in their native tissue context. Here we present the first comprehensive, independent evaluation of Atera, a new spatial whole transcriptome platform, compared against Xenium on adjacent sections of human ductal carcinoma in situ (DCIS). We show that Atera enables granular cell-state annotation and resolves rare cell populations, which we experim...

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Literature Corpus work: a8a79cbf-ba4a-5149-a130-e48cd6fe8474
DOI: 10.64898/2026.08.03.741871

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