Article

Evaluation of the OsTIR1 and AtAFB2 AID systems for chromatin protein degradation in mammalian cells

2021-03-15

Abstract excerpt

<h4>ABSTRACT</h4> Auxin-inducible degron (AID) system is a promising tool for dynamic protein degradation. In mammalian cells, this approach has become indispensable to study fundamental molecular functions, such as replication, chromatin dynamics or transcription, that are otherwise difficult to dissect. We present evaluation of the two prominent AID systems based on OsTIR1 and AtAFB2 auxin receptor F-box protei...

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Literature Corpus work: a7ca17fe-72aa-5d2f-8abc-f120b630d115
DOI: 10.1101/2021.03.15.435352

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