Article

Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define diagnostic biosignatures for Parkinson’s Disease

2022-01-24

Abstract excerpt

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for both familial and sporadic forms of Parkinson’s disease (PD). However, compared to cancer, overall lower genetic mutations contribute to the cause of PD, propelling the search for protein biomarkers for early detection of the disease. Utilizing 141 urine samples from four groups, healthy individuals (control...

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Literature Corpus work: a7bde487-855b-5375-904d-6cbbd26b7394
DOI: 10.1101/2022.01.18.22269096

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