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Article

Urinary proteome profiling for stratifying patients with familial Parkinson's disease.

EMBO molecular medicine - 5 Mar 2021

Virreira Winter Sebastian, Karayel Ozge, Strauss Maximilian T, Padmanabhan Shalini, Surface Matthew, Merchant Kalpana, Alcalay Roy N, Mann Matthias

Abstract excerpt

The prevalence of Parkinson's disease (PD) is increasing but the development of novel treatment strategies and therapeutics altering the course of the disease would benefit from specific, sensitive, and non-invasive biomarkers to detect PD early. Here, we describe a scalable and sensitive mass spectrometry (MS)-based proteomic workflow for urinary proteome profiling. Our workflow enabled the reproducible...

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Identifiers

PMID: 33481347
DOI: 10.15252/emmm.202013257
PMCID: PMC7933820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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