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The Cellular and Extra-Cellular Proteomic Signature of Human Dopaminergic Neurons Carrying the LRRK2 G2019S Mutation

2024-09-20

Abstract excerpt

<h4>ABSTRACT</h4> Extracellular vesicles are easily accessible in various biofluids and allow the assessment of disease-related changes of the proteome. This has made them a promising target for biomarker studies, especially in the field of neurodegeneration where access to diseased tissue is very limited. Genetic variants in the LRRK2 gene have been linked to both familial and sporadic forms of Parkinson’s disea...

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Literature Corpus work
f56642f8-5915-5ceb-93d4-498fea608f47
DOI
10.1101/2024.09.20.614055
Open publication

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The Cellular and Extra-Cellular Proteomic Signature of Human Dopaminergic Neurons Carrying the LRRK2 G2019S MutationDOI 10.1101/2024.09.20.614055
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