Article

Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically

2020-07-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> MEG3 is abnormally down-regulated in most tumors and inhibits tumorigenesis. <bold>Methods: </bold>Gene infection, Western blotting and tumorigenesis test <italic>in vitro </italic>and <italic>in vivo</italic> were performed to analyze the signaling pathway.<bold> </bold><bold>Results:</bold> MEG3 increased the loading of P300 and RNA polymerase II onto the prom...

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Literature Corpus work: a7882105-8a41-57ab-9a8b-4ef3a644eb84
DOI: 10.21203/rs.3.rs-42251/v1

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