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Article

Epigenetic regulation of hTERT promoter in hepatocellular carcinomas

1 Jan 1992

Abstract excerpt

Although hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, the molecular pathogenesis of the disease has not been elucidated. Several studies have shown that telomerase activity and hTERT expression are increased in HCCs. In the present study we tried to elucidate hTERT transcriptional and epigenetic regulatory mechanisms in HCC. hTERT expression was tested by real-time PCR and DNA...

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Share to Epigenetics and DNA Methylation
Share to Genomics and Chromatin Dynamics
Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 19148473
DOI: 10.3892/ijo_00000162

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