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Telomerase: a good target in hepatocellular carcinoma? An overview of relevant preclinical data

2 Sept 2022

Abstract excerpt

INTRODUCTION: The expression of telomerase reverse transcriptase (TERT) in liver is restricted to rare cells, that are able to replace senescent hepatocytes and regenerate tissue in response to hepatic damage, while becoming extinguished in differentiated progeny cells. TERT gene is permanently activated in liver neoplasms from the very early stage of the hepatocarcinogenesis mainly through the accumulation of...

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PMID: 36369706
DOI: 10.1080/14728222.2022.2147062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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