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Article

Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytes

26 Jan 2019

Abstract excerpt

modelling. Cardiovascular disease is the greatest cause of mortality worldwide but encompasses rarer disorders of conduction and myocardial function for which a cellular model of study is ideal. Although methods to differentiate iPSCs into beating cardiomyocytes (iPSC-CMs) have recently been adequately optimized and commercialized, the resulting cells remain largely immature with regards to their structure and...

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PMID: 30705713
DOI: 10.4252/wjsc.v11.i1.33

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