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Multi-omic analysis reveals maturation programs in human pluripotent stem cell-derived cardiomyocytes during long-term culture

2026-06-27

Abstract excerpt

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold tremendous promise for disease modeling, drug discovery, and cardiac regenerative therapies. However, the immature phenotype of hPSC-CMs remains a major barrier limiting their translational utility. Here, we performed integrated multi-omic profiling to identify molecular pathways and regulatory programs associated with hPSC-CM maturation during lon...

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Literature Corpus work
142db591-71fb-5e79-9df0-c9766434ddd0
DOI
10.64898/2026.06.26.734802
Open publication

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Multi-omic analysis reveals maturation programs in human pluripotent stem cell-derived cardiomyocytes during long-term cultureDOI 10.64898/2026.06.26.734802
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