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Recent advances in regulating the proliferation or maturation of human-induced pluripotent stem cell-derived cardiomyocytes

30 Aug 2023

Abstract excerpt

In the last decade, human-induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM)-based cell therapy has drawn broad attention as a potential therapy for treating injured hearts. However, mass production of hiPSC-CMs remains challenging, limiting their translational potential in regenerative medicine. Therefore, multiple strategies including cell cycle regulators, small molecules, co-culture systems, and...

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PMID: 37649113
DOI: 10.1186/s13287-023-03470-w

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