Article
Human-induced pluripotent stem cells in cardiovascular research: current approaches in cardiac differentiation, maturation strategies, and scalable production.
Cardiovascular research - 7 Jan 2022
Thomas Dilip, Cunningham Nathan J, Shenoy Sushma, Wu Joseph C
Abstract excerpt
Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based on inherent biological makeup, lifestyle, and exposure to environmental risk factors. These variables mean that therapeutic interventions may not provide the same benefit to every patient. In the context of CVDs, human-induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) offer an opportunity to model CVDs in a...
Topics
- Biomedical Research
- Cardiology
- Cardiotoxicity
- Cardiovascular Agents
- Cardiovascular Diseases
- Cell Culture Techniques, Three Dimensional
- Cell Differentiation
- Cell Proliferation
- Clinical Decision-Making
- Drug Discovery