Article

Maturation of human induced pluripotent stem cell-derived cardiomyocytes for modeling hypertrophic cardiomyopathy

2020-01-17

Abstract excerpt

<h4>Rationale</h4> Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are a powerful platform for biomedical research. However, they are immature, which is a barrier to modeling adult-onset cardiovascular disease. <h4>Objective</h4> We sought to develop a simple method which could drive cultured hiPSC-CMs towards maturity across a number of phenotypes. <h4>Methods and results</h4> Cells were...

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Literature Corpus work: 58eb9769-02c0-5f21-8622-051e9490d0ad
DOI: 10.1101/2020.01.16.909598

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