Article
Aging-associated changes in transcriptional elongation influence metazoan longevity
2019-08-08
Abstract excerpt
Physiological homeostasis becomes compromised during aging, as a result of impairment of cellular processes, including transcription and RNA splicing. However, the molecular mechanisms leading to the loss of transcriptional fidelity are so far elusive, as are ways of preventing it. Here, we profiled and analyzed genome-wide, aging-related changes in transcriptional processes across different organisms: nematode wo...
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Identifiers and source
- Literature Corpus work
- a761ba20-1722-56d4-809f-9f0fe028b057
- DOI
- 10.1101/719864