Article
Translational suppression via IFG-1/eIF4G confers resistance to stress-induced RNA alternative splicing in <i>Caenorhabditis elegans</i>
2021-11-29
Abstract excerpt
<h4>SUMMARY</h4> Splicing of pre-mRNA is an essential process for dividing cells and splicing defects have been linked to aging and various chronic diseases. Environmental stress has recently been shown to alter splicing fidelity and molecular mechanisms that protect against splicing disruption remains unclear. Using an in vivo RNA splicing reporter, we performed a genome-wide RNAi screen in Caenorhabditis eleg...
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Identifiers and source
- Literature Corpus work
- 6c64a343-326c-57b3-b646-f7c0d713a1bc
- DOI
- 10.1101/2021.11.29.470369
