Article

Determinants shaping the nanoscale architecture of the mouse rod outer segment

2021-08-20

Abstract excerpt

The unique membrane organization of the rod outer segment (ROS), the specialized sensory cilium of rod photoreceptor cells, provides the foundation for phototransduction, the initial step in vision. ROS architecture is characterized by a stack of identically shaped and tightly packed membrane disks loaded with the visual receptor rhodopsin. A wide range of genetic aberrations compromise ROS ultrastructure, impairi...

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Literature Corpus work: a744cb11-4e4c-51a3-9a50-d8d37af51182
DOI: 10.1101/2021.08.18.456753

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