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Article

Rsph4a is essential for the triplet radial spoke head assembly of the mouse motile cilia.

PLoS genetics - 1 Mar 2020

Yoke Hiroshi, Ueno Hironori, Narita Akihiro, Sakai Takafumi, Horiuchi Kahoru, Shingyoji Chikako, Hamada Hiroshi, Shinohara Kyosuke

Abstract excerpt

Motile cilia/flagella are essential for swimming and generating extracellular fluid flow in eukaryotes. Motile cilia harbor a 9+2 arrangement consisting of nine doublet microtubules with dynein arms at the periphery and a pair of singlet microtubules at the center (central pair). In the central system, the radial spoke has a T-shaped architecture and regulates the motility and motion pattern of cilia. Recent...

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Identifiers

PMID: 32203505
DOI: 10.1371/journal.pgen.1008664
PMCID: PMC7147805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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