Article

The connecting cilium inner scaffold provides a structural foundation to maintain photoreceptor integrity

2021-08-28

Abstract excerpt

Retinal degeneration is a leading cause of human blindness due to progressive loss of ciliated photoreceptors cells. While this degradation can be associated with cohesion defects of the microtubule-based connecting cilium (CC) structure, the underlying mechanism is not understood. Here, using expansion microscopy and electron microscopy, we reveal the molecular architecture of the CC and demonstrate that microtub...

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Identifiers and source

Literature Corpus work: cbaf2ef2-4956-5366-ac8a-17aa100ded58
DOI: 10.1101/2021.08.27.457921

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