Article
Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.
Human molecular genetics - 15 Jun 2016
Nguyen O N Phuong, Böhm Sybille, Gießl Andreas, Butz Elisabeth S, Wolfrum Uwe, Brandstätter Johann H, Wahl-Schott Christian, Biel Martin, Becirovic Elvir
Abstract excerpt
Peripherin-2 is a glycomembrane protein exclusively expressed in the light-sensing compartments of rod and cone photoreceptors designated as outer segments (OS). Mutations in peripherin-2 are associated with degenerative retinal diseases either affecting rod or cone photoreceptors. While peripherin-2 has been extensively studied in rods, there is only little information on its supramolecular organization and...
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