Article

Centriole and transition zone structures in photoreceptor cilia revealed by cryo-electron tomography

2023-10-06

Abstract excerpt

Primary cilia mediate sensory signaling in multiple organisms and cell types but have structures adapted for specific roles. Structural defects in them lead to devastating diseases known as ciliopathies in humans. Key to their functions are structures at their base: the basal body, the transition zone, the “Y-shaped links” and the “ciliary necklace”. We have used cryo-electron tomography with subtomogram averaging...

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Literature Corpus work: 749dd16e-5b69-5bf5-bdbb-cab0a76be0bf
DOI: 10.1101/2023.10.05.560879

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