Article

<i>Ybx1</i> guides C/EBPα and cBAF chromatin-remodeling complex to promote adipogenic gene expression in steatotic hepatocytes

2024-10-26

Abstract excerpt

<h4>Summary</h4> Excessive lipid accumulation by hepatocytes underlies the pathogenesis of metabolic-dysfunction associated steatotic liver disease (MASLD) and metabolic-dysfunction associated steatohepatitis (MASH) from the earliest stages of the disease. How liver cells regulate the commitment to storing large volumes of fat despite resulting tissue damage is not well understood. Here, we show Y box-binding pr...

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Literature Corpus work: a73b9ed8-bac6-51c0-8e48-8dc642e8db28
DOI: 10.1101/2024.10.25.620017

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<i>Ybx1</i> guides C/EBPα and cBAF chromatin-remodeling complex to promote adipogenic gene expression in steatotic hepatocytesDOI 10.1101/2024.10.25.620017Read

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