Article

Identification of a novel deFADding activity in 5’ to 3’ exoribonucleases

2022-05-10

Abstract excerpt

<h4>ABSTRACT</h4> Identification of metabolite caps including FAD on the 5’ end of RNA has uncovered a previously unforeseen intersection between cellular metabolism and gene expression. To understand the function of FAD caps in cellular physiology, we characterised the proteins interacting with FAD caps in budding yeast. Here we demonstrate that highly conserved 5’-3’ exoribonucleases, Xrn1 and Rat1, physically...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a6c592c9-f47e-56c2-bf5e-05a536fdf00c
DOI: 10.1101/2022.05.10.491372

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of a novel deFADding activity in 5’ to 3’ exoribonucleasesDOI 10.1101/2022.05.10.491372Read

Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity.Semantic proximity Read

XRN 5'→3' exoribonucleases: structure, mechanisms and functions.Semantic proximity Read

Identification and <i>in vitro</i> characterization of UDP-GlcNAc-RNA cap-modifying and decapping enzymesSemantic proximity Read

Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.Semantic proximity Read

Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay.Semantic proximity Read

A conserved viral RNA fold enables nuclease resistance across kingdoms of lifeSemantic proximity Read

Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAsSemantic proximity Read

"NAD-capQ" detection and quantitation of NAD caps.Semantic proximity Read

A mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing.Semantic proximity Read

RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities.Semantic proximity Read

Regulation and surveillance of normal and 3'-extended forms of the yeast aci-reductone dioxygenase mRNA by RNase III cleavage and exonucleolytic degradation.Semantic proximity Read

Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae.Semantic proximity Read