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Article

Regulation and surveillance of normal and 3'-extended forms of the yeast aci-reductone dioxygenase mRNA by RNase III cleavage and exonucleolytic degradation.

The Journal of biological chemistry - 12 Aug 2005

Zer Cindy, Chanfreau Guillaume

Abstract excerpt

Aci-reductone dioxygenases are key enzymes in the methionine salvage pathway. The mechanisms by which the expression of this important class of enzymes is regulated are poorly understood. Here we show that the expression of the mRNA encoding the yeast aci-reductone dioxygenase ADI1 is controlled post-transcriptionally by RNase III cleavage. Cleavage occurs in a large bipartite stem loop structure present in the...

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Identifiers

PMID: 15967792
DOI: 10.1074/jbc.M505913200

Genes

ADI1

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