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Article

RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities.

Nature communications - 18 Dec 2017

Sikorska Natalia, Zuber Hélène, Gobert Anthony, Lange Heike, Gagliardi Dominique

Abstract excerpt

The RNA exosome provides eukaryotic cells with an essential 3'-5' exoribonucleolytic activity, which processes or eliminates many classes of RNAs. Its nine-subunit core (Exo9) is structurally related to prokaryotic phosphorolytic exoribonucleases. Yet, yeast and animal Exo9s have lost the primordial phosphorolytic capacity and rely instead on associated hydrolytic ribonucleases for catalytic activity. Here, we...

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Identifiers

PMID: 29255150
DOI: 10.1038/s41467-017-02066-2
PMCID: PMC5735172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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