Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses

16 Mar 2010

Abstract excerpt

Dendritic cells (DCs) play a crucial role in the development of protective immunity to malaria. However, it remains unclear how malaria parasites trigger immune responses in DCs. In this study, we purified merozoites, food vacuoles, and parasite membrane fragments released during the Plasmodium falciparum schizont burst to homogeneity and tested for the activation of bone marrow-derived DCs from wild-type and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20231693
DOI: 10.4049/jimmunol.0903824

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune ResponsesPMID 20231693Read ↗

The Nucleosome (Histone-DNA Complex) Is the TLR9-Specific Immunostimulatory Component of Plasmodium falciparum That Activates DCsSemantic proximity Read ↗

Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infectionsSemantic proximity Read ↗

Dendritic cell responses to Plasmodium falciparum in a malaria-endemic settingSemantic proximity Read ↗

Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malariaSemantic proximity Read ↗

Dendritic cell function and antigen presentation in malariaSemantic proximity Read ↗

TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions.Semantic proximity Read ↗

Direct activation of human dendritic cells by particle-bound but not soluble MHC class II ligand.Semantic proximity Read ↗

Dendritic cell responses to Plasmodium falciparum in a malaria-endemic setting.Semantic proximity Read ↗

Activation of human dendritic cells is modulated by components of the outer membranes of Neisseria meningitidis.Semantic proximity Read ↗

Bacterial Ghosts of Escherichia coli Drive Efficient Maturation of Bovine Monocyte-Derived Dendritic Cells.Semantic proximity Read ↗

HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles.Semantic proximity Read ↗

Anisakis pegreffii impacts differentiation and function of human dendritic cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.