Article

<i>Plasmodium falciparum</i> malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

2020-10-21

Abstract excerpt

In malaria-naïve children and adults, Plasmodium falciparum -infected red blood cells ( Pf -iRBCs) trigger fever and other symptoms of systemic inflammation. However, in endemic areas where individuals experience repeated Pf infections over many years, the risk of Pf -iRBC-triggered inflammatory symptoms decreases with cumulative Pf exposure. The molecular mechanisms underlying these clinical observations rem...

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Literature Corpus work: 5c2f2e2c-5583-5015-9a91-35e0060c7dd1
DOI: 10.1101/2020.10.21.346197

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