Article
Metabolites: deciphering the molecular language between DCs and their environment.
Seminars in immunopathology - 1 Feb 2017
Minarrieta Lucía, Ghorbani Peyman, Sparwasser Tim, Berod Luciana
Abstract excerpt
Dendritic cells (DCs) determine the outcome of the immune response based on signals they receive from the environment. Presentation of antigen under various contexts can lead to activation and differentiation of T cells for immunity or dampening of immune responses by establishing tolerance, primarily through the priming of regulatory T cells. Infections, inflammation and normal cellular interactions shape DC...
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