Article
Cellular nucleic acid-binding protein (CNBP) dependent cytokine programming shapes host defense against <i>Plasmodium</i> infection
2026-06-03
Abstract excerpt
During blood-stage Plasmodium infection, effective immune control hinges on the IL12β-IFN-γ axis, yet how this pathway is transcriptionally tuned in vivo remains incompletely defined. Innate sensing of parasite-derived ligands by pattern-recognition receptors, including Toll like receptors, in dendritic cells and macrophages induces IL-12β production that drives IFN-γ mediated control of infection. Emerging evid...
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Identifiers and source
- Literature Corpus work
- 4d690eb3-a21e-5783-be99-3c0b88e69855
- DOI
- 10.64898/2026.06.01.729202
