Article
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
Blood - 3 Mar 2011
Bosco Maria Carla, Pierobon Daniele, Blengio Fabiola, Raggi Federica, Vanni Cristina, Gattorno Marco, Eva Alessandra, Novelli Francesco, Cappello Paola, Giovarelli Mirella, Varesio Luigi
Abstract excerpt
Dendritic cells (DCs) are a heterogeneous group of professional antigen-presenting cells functioning as sentinels of the immune system and playing a key role in the initiation and amplification of innate and adaptive immune responses. DC development and functions are acquired during a complex dif...
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