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Article

Multiplex Imaging for Cell Phenotyping of Early Human Atherosclerosis.

Journal of the American Heart Association - 18 Jun 2024

Elishaev Maria, Li Boaz, Zhou Annie, Salim Kevin, Leeper Nicholas J, Francis Gordon A, Lai Chi, Wang Ying

Abstract excerpt

BACKGROUND: Previous studies using animal models and cultured cells suggest that vascular smooth muscle cells (SMCs) and inflammatory cytokines are important players in atherogenesis. Validating these findings in human disease is critical to designing therapeutics that target these components. Multiplex imaging is a powerful tool for characterizing cell phenotypes and microenvironments using biobanked human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38842292
DOI: 10.1161/JAHA.123.034990
PMCID: PMC11255771

Genes

CD68

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