Article

Characterizing the skeletal muscle immune microenvironment for sarcopenia using transcriptome analysis and histological validation

2024-02-24

Abstract excerpt

Sarcopenia is a condition characterized by the age-related loss of skeletal muscle mass and function. The pathogenesis of the disease is influenced by chronic low-grade inflammation. However, the specific changes in the immune landscape changes of sarcopenic muscle are not yet fully understood. To gain insights into the immune cell composition and interactions, we combined single-nuclei RNA sequencing data, bulk R...

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Literature Corpus work: a66de005-ae1f-536c-9cb9-7ad692345b88
DOI: 10.1101/2024.02.23.24303270

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