Article
Single nuclei profiling identifies cell specific markers of skeletal muscle aging, sarcopenia and senescence
2021-01-26
Abstract excerpt
Aging is accompanied by a loss of muscle mass and function, termed sarcopenia, which causes numerous morbidities and economic burdens in human populations. Mechanisms implicated in age-related sarcopenia include inflammation, muscle stem cell depletion, mitochondrial dysfunction and loss of motor neurons, but whether there are key drivers of sarcopenia is not yet known. To gain deeper insights into age-related sar...
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Identifiers and source
- Literature Corpus work
- e9da77c4-398c-5d65-ad1c-1d0872a4e58d
- DOI
- 10.1101/2021.01.22.21250336