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Article

Characterizing the skeletal muscle immune microenvironment for sarcopenia: insights from transcriptome analysis and histological validation

4 Jul 2024

Abstract excerpt

Background: Sarcopenia is a condition characterized by the age-related loss of skeletal muscle mass and function. The pathogenesis of the disease is influenced by chronic low-grade inflammation. However, the specific changes in the immune landscape changes of sarcopenic muscle are not yet fully understood. Methods: To gain insights into the immune cell composition and interactions, we combined single-nucleus RNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39026669
DOI: 10.3389/fimmu.2024.1414387

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