Single Cell RNA ‐Seq Identifies Cell Subpopulations Contributing to Idiopathic Pulmonary Fibrosis in Humans

Abstract excerpt

The cell populations, particularly subpopulations, involved in the onset and progression of idiopathic pulmonary fibrosis (IPF) remain incompletely understood. This study employed single-cell RNA-seq to identify cell populations and subpopulations with significantly altered proportions in the lungs of patients with IPF. In IPF lungs, endothelial cell proportions were significantly increased, while alveolar...

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• Share to Extracellular vesicles in disease
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