Back to search

Article

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

2023-04-18

Abstract excerpt

<h4>ABSTRACT</h4> The monocytic/macrophage system is essential for skeletal muscle homeostasis, but its dysregulation contributes to the pathogenesis of muscle degenerative disorders. Despite our increasing knowledge of the role of macrophages in degenerative disease, it still remains unclear how macrophages contribute to muscle fibrosis. Here, we used single-cell transcriptomics to determine the molecular attrib...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3dd97730-018a-5779-8523-4894aa6e641a
DOI
10.1101/2023.04.18.537253
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosisDOI 10.1101/2023.04.18.537253
Select a neighboring publication to make it the new centre.