Article

Hyperammonemia-derived Neurovascular Inflammation Mediated by MAO-A and δ- Secretase in Neurodegenerative Brain Models

2024-10-14

Abstract excerpt

<title>Abstract</title> <p>Ammonia is a potent neurotoxin that can lead to hepatic encephalopathy (HE), a severe neurological condition associated with cerebral edema. Recent studies have increasingly shown an association between hepatic encephalopathy, particularly cerebral edema and tauopathy, yet no existing model adequately explains the underlying mechanism. Here, we report that hyperammonemia triggers neurov...

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Literature Corpus work: a6593198-3f94-56ca-a6fa-d252d411b07c
DOI: 10.21203/rs.3.rs-5242396/v1

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