Article

Ammonia Induced Microglial Activation Modulates Connexin 43 and Aquaporin 4 Expression in Astrocyte-microglia Co-culture Model

2020-09-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Hepatic encephalopathy (HE) is a neurological complication resulting from acute or chronic liver disease. Hyperammonemia leading to astrocyte swelling and cerebral edema in combination with neuroinflammation including microglia activation, mainly contribute to the pathogenesis of HE. However, little is known about microglia and their inflammatory response, as wel...

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Literature Corpus work: cf106777-2ce8-5e0c-a0aa-581b925f9778
DOI: 10.21203/rs.3.rs-55598/v1

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