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Cellular antibody affinity-based CRISPR Screening identifies JUNB as a broadly acting anti-viral factor

2025-06-13

Abstract excerpt

CRISPR screening is a powerful approach to identify genetic perturbations that impact viral infection. However, most virus-focused CRISPR screens utilize selection strategies that limit the ability to identify genes important for infection. Here, we developed a novel CRISPR screening pipeline to identify cellular determinants of Human Cytomegalovirus infection based on virally induced remodeling of cellular antibo...

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Literature Corpus work
a1bc5419-8fb1-5012-a7d8-344b87f01e1b
DOI
10.1101/2025.06.12.659131
Open publication

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Cellular antibody affinity-based CRISPR Screening identifies JUNB as a broadly acting anti-viral factorDOI 10.1101/2025.06.12.659131
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