Article

Type I IFN in Glomerular Disease: Scarring beyond the STING

2024-01-03

Abstract excerpt

The field of nephrology has recently directed a considerable amount of attention towards the stimulator of interferon genes (STING) molecule since it appears to be a potent driver of chronic kidney disease (CKD). STING and its activator, the cyclic GMP-AMP synthase (cGAS) are among the most relevant inducers that promote the expression of type I interferons (IFN-Is). These cytokines have been long recognized as pa...

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Literature Corpus work: a579b594-bc87-56e5-a046-1cf7a73c3128
DOI: 10.20944/preprints202401.0102.v1

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