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Advances in cGAS-STING Signaling Pathway and Diseases

3 Feb 2022

Abstract excerpt

Pathogens can produce conserved pathogen-associated molecular patterns (PAMPs) after invading the body, which can be specifically recognized by host pattern recognition receptors (PRRs). In recent years, it has been found that cytoplasmic DNA receptors recognize exogenous DNA inducing activation of interferon 1 (IFN1), which is a rapid advance in various research areas. The cyclic GMP-AMP synthase (cGAS)...

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PMID: 35186921
DOI: 10.3389/fcell.2022.800393

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