Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular and spatial mechanisms governing STING signalling

25 Nov 2020

Abstract excerpt

Detection of microbial nucleic acids via innate immune receptors is critical for establishing host defence against pathogens. The DNA-sensing cGAS-STING pathway has gained increasing attention in the last decade as a key pathway for combating viral and bacterial infections. cGAS-STING activation primarily promotes the secretion of antiviral type I IFNs via the key transcription factor, IRF3. In addition,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to interferon and immune responses
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33237620
DOI: 10.1111/febs.15640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular and spatial mechanisms governing STING signallingPMID 33237620Read ↗

Membrane traffic governs the STING inflammatory signallingSemantic proximity Read ↗

Function and regulation of cGAS-STING signaling in infectious diseasesSemantic proximity Read ↗

STING: a multifaced player in cellular homeostasis.Semantic proximity Read ↗

IUPHAR ECR review: The cGAS-STING pathway: Novel functions beyond innate immune and emerging therapeutic opportunitiesSemantic proximity Read ↗

The cGAS-STING Pathway: A Promising Immunotherapy TargetSemantic proximity Read ↗

Advances in cGAS-STING Signaling Pathway and DiseasesSemantic proximity Read ↗

The STING in the Tail for Cytosolic DNA–Dependent Activation of IRF3Semantic proximity Read ↗

STING trafficking as a new dimension of immune signalingSemantic proximity Read ↗

cGAS and STING: At the intersection of DNA and RNA virus-sensing networksSemantic proximity Read ↗

cGAMP the travelling messengerSemantic proximity Read ↗

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory ResponseSemantic proximity Read ↗

Regulation of the cGAS-STING PathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.